HRT Treatment

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With over 15 years of experience in women’s health, Dr. Jadoon’s expertise is nothing short of exceptional. Holding a prestigious Certification of Completion of Training (CCT) in Obstetrics and Gynaecology from Oxford Deanery and an MSc in Healthcare Management, she brings a unique blend of clinical excellence and visionary leadership.
Dr. Jadoon’s work spans the globe – from NHS research to collaborating with the World Health Organization on quality improvement projects. Her research was around implementation of the 10 Group Robson Classification to optimise c-section rate, cementing her status as a thought leader in women’s health.

Prescribed treatments

Hormone replacement therapy (HRT)

See the information on HRT below.

Non-hormonal medical treatment

Nonhormonal medical treatments, which would need to be prescribed by your doctor, include clonidine or gabapentin for hot flushes.

Psychological treatments

Cognitive behavioural therapy (CBT) is a type of psychological treatment. You may be offered CBT for low mood or anxiety related to menopause

Hormone replacement therapy (HRT)

HRT is the most common form of prescribed treatment for menopausal symptoms. It helps to replace the hormone estrogen in your body, which decreases around your menopause. You may sometimes also need other hormones (such as progestogen and testosterone) that your body is no longer producing.

If you are interested in taking HRT, your healthcare professional should discuss the benefits and risks with you before you start the treatment. This discussion should cover both the shortterm (over the next 5 years) and the longer term (beyond the next 5 years) benefits and risks for you.

You should also be informed about available alternatives to HRT along with their benefits and risks.

What are the different types of HRT?

The type of HRT that you are prescribed depends on your individual situation. If you have a uterus (womb) then a combination of estrogen and progestogen HRT (combined HRT) would be recommended.

Estrogen alone can cause abnormal thickening of the lining of your uterus, which can lead to bleeding.Adding progestogen will prevent this. Progestogen may be given in the form of tablets, patches or a hormonecontaining coil.

If combined HRT is started before you have the menopause or within 12 months of your last period then you will be offered a ‘cyclical’ combined HRT, which should give you regular monthly withdrawal bleeds.
If you start combined HRT more than 12 months after your last period, you may be offered ‘continuous’ combined HRT (bleedfree HRT). You may experience some vaginal bleeding in the first 3 months, but after this it should stop.

If you have had a hysterectomy then you will be offered estrogenonly HRT.

Women who notice a low sex drive after the menopause may be offered another hormone called testosterone. This is a hormone linked to sex drive in both men and women.

HRT is available as oral tablets, skin patches, injections, body gel or spray, or vaginal ring, cream or pessary.

Is HRT safe and does it work?

The effects of HRT have been studied worldwide and research shows that, for most women, HRT works and is safe

What are the benefits of HRT?
  • It is an effective treatment for hot flushes and low mood associated with the menopause.
  • It can improve sexual desire and reduce vaginal dryness.
  • It helps keep your bones strong by preventing osteoporosis
What are the risks of HRT?
  • HRT with estrogen alone (used for women who have no uterus) is associated with little or no increased risk of breast cancer.
  • HRT with estrogen and progestogen can increase your risk of breast cancer. This risk is higher the longer you stay on it and reduces when you stop HRT.
  • Your individual risk of developing breast cancer depends on underlying risk factors, such as your body weight and your drinking and smoking habits.
  • HRT taken as a tablet increases your risk of developing a blood clot, which is not the case if HRT is taken as a patch or gel.
  • HRT in tablet form slightly increases your risk of stroke, although the overall risk of stroke is very low if you are under the age of 60 years.

Your healthcare professional should discuss your individual risks based on the research evidence at your consultation.

Can I still have HRT if I have had breast cancer or clots in my legs or lungs?

HRT may still be an option for you and you should discuss this with your healthcare professional, who may seek advice or refer you to a menopause specialist.

Can I take HRT if I have diabetes or high blood pressure?

HRT should not affect your blood sugar control. If you are diabetic or have very high blood pressure, your healthcare professional may consult with a specialist before prescribing HRT

Would taking HRT prevent dementia?

It is not known whether HRT affects the development of dementia.

Do I still need to use contraception when taking HRT?

HRT does not provide contraception. You need to continue using contraception for 1 year after your last period if this happens after the age of 50 years. If your last period happens before you are 50 years of age then you need to continue using contraception for 2 years.

When should I seek advice after starting HRT?

You should have a review appointment with your healthcare professional after 3 months of starting or changing HRT, and then yearly thereafter if all remains well.

You may notice some vaginal bleeding in the first 3 months of starting or changing HRT, but if you experience any bleeding after 3 months then you should see your healthcare professional straight away.

How long can I take HRT for?

There are no set time limits for how long you can be on HRT. The benefits and risks of taking HRT will depend on your individual situation, and your healthcare professional should discuss these with you.

How do I stop HRT?

You can stop your HRT suddenly or reduce gradually before stopping it. The chances of your symptoms coming back is the same either way.

Do I need a referral to a menopause specialist?

If your menopausal symptoms are not responding to HRT or there are reasons why HRT may not be considered safe for you, your healthcare professional may seek advice from, or refer you to, a menopause specialist.

Which treatment is best for my hot flushes and night sweats?

If you are troubled with hot flushes and night sweats, you should be offered HRT after discussing its benefits and risks. You may wish to discuss the alternative options described above with your healthcare professional.

Which treatment is best for my low mood?

HRT is an effective treatment for low mood. CBT is also helpful in treating low mood and anxiety related to the menopause.
Low mood as a result of the menopause is different from depression. Antidepressants are not helpful unless you have been diagnosed with depression. If you are on antidepressants, it is safe to take HRT as well as use CBT.

Which treatment is best for my lack of interest in sex?

HRT containing estrogen and/or progestogen may be helpful as treatment for low sexual desire during menopause. If this doesn’t work then you should talk to your healthcare professional about whether to  consider another hormone called testosterone, which is linked to sex drive in both men and women.

Which treatment is best for my vaginal dryness?

Many women find using vaginal moisturisers and lubricants helpful for vaginal dryness. Ask your healthcare professional about the best one for you.
Estrogen given vaginally in the form of a tablet, cream or ring is effective in treating vaginal dryness. Lowdose vaginal estrogens can be used for as long as you need to and can also be safely used in combination with HRT. These can also reduce bladder infections and help urinary symptoms. If you experience any unexpected vaginal bleeding, you should tell your healthcare professional. Other forms of HRT can also help with vaginal dryness.

What is premature menopause (premature ovarian insufficiency) and what causes it?

This is when you go through the menopause before the age of 40 years. Usually, no cause is found for this. It can be caused by surgery on the ovaries, chemotherapy, or radiotherapy to the pelvis. It can also run in families. Other less common causes include chromosomal problems, such as Turner syndrome, and autoimmune disease when the body’s immune system attacks the developing eggs.

How is premature menopause diagnosed?

If your periods become infrequent or stop before the age of 40 years and/or you experience menopausal symptoms, you should see your healthcare professional. You will be offered blood tests to measure your hormone levels to help diagnose premature menopause. The diagnosis is made after two blood tests are performed 4–6 weeks apart.

Are there any health risks related to premature menopause?

You are likely to notice the symptoms of menopause, such as hot flushes and mood changes. There is also an increased risk of developing osteoporosis and cardiac disease in later life. Osteoporosis can lead to broken bones if not treated. Premature menopause will affect your fertility, and your chance of getting pregnant will be greatly reduced.

What is the treatment for premature menopause?

Treatment for premature menopause involves the replacement of hormones in the form of either HRT or the combined oral contraceptive pill. Both are effective in treating hot flushes and keeping your bones strong.
While the combined oral contraceptive pill has the advantage of also providing contraception, HRT is a safer option if you have high blood pressure.
It is important for you to continue the treatment at least until the average age of natural menopause. By taking HRT, you are simply replacing the hormones your body is lacking, and so there are no added risks.
If you are thinking about getting pregnant, you will need a referral to a fertility specialist. Your healthcare professional may also suggest referral to a menopause specialist.

Further information

RCOG Menopause Hub: www.rcog.org.uk/en/patients/menopause

Menopause Matters: https://menopausematters.co.uk

Women’s Health Concern: www.womens-health-concern.org/

A full list of useful organisations (including the above) is available on the RCOG website at:www.rcog.org.uk/en/patients/other-sources-of-help/

Source and acknowledgement

This information has been developed by the RCOG Patient Information Committee. It is based on the National Institute for Health and Care Excellence (NICE) guideline 23 on Menopause: Diagnosis and Management, published in November 2015. The guideline contains a full list of the sources of evidence we have used. You can find it online at: www.nice.org.uk/guidance/ng23. This information has been reviewed before publication by women attending clinics in London, Poole and Bury St Edmunds, by the RCOG Women’s Network and by the RCOG Women’s Voices Involvement Panel.

Alternatives to hormone replacement therapy (HRT)

Find out about other ways of treating menopause symptoms if you cannot take HRT or prefer not to take it.

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